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Fusion Medical
aesthetic clinic singapore
+65 8802 1542
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Fusion Medical
aesthetic clinic singapore
Gloved doctor assessing the skin on a patient’s cheek before PDRN treatment

Salmon DNA skin booster · Singapore

PDRN injections: salmon DNA to support skin repair.

If your skin is feeling tired, dull or showing signs of ageing, PDRN may be the gentle skin-repairing treatment you’ve been looking for.

What is a PDRN injection?

Salmon DNA fragments to support skin repair.

PDRN injections use fragments of DNA derived from salmon, a source known for its biocompatibility with human skin. Placed in the superficial layer of the skin, these molecules help support its natural healing and regeneration process, to improve skin quality from within.

PDRN stands for polydeoxyribonucleotide. It is often recommended when skin has become dull, sensitive or weakened over time, and some people use it to maintain skin health as part of a long-term skincare routine.

If you are comparing it with our PN injectable (polynucleotides from Italian trout), the FAQ below sets out how the two differ. Your doctor will explain which one suits your skin.

  • Salmon DNA — fragments known for their biocompatibility with skin
  • Skin repair — supports natural healing and regeneration
  • Superficial — tiny injections by fine needle or injector gun
  • Minimal downtime — most people resume daily activities quickly
Skin booster injector gun and its console on a treatment trolley at Fusion Medical
PDRN is placed with a fine needle or an injector gun, after numbing cream.

How it works

How do PDRN injections work?

PDRN places fragments of salmon DNA in the superficial layer of the skin, where they help support its natural healing and regeneration process. Over a course of treatments, the aim is better skin quality (texture, elasticity, hydration and radiance) rather than instant volume.

See the treatment journey

Illustration of DNA-fragment chains and hydration droplets within the dermis

Salmon DNA fragments

The active ingredient is polydeoxyribonucleotide: DNA fragments derived from salmon.

Illustrated cross-section of skin layers, from the surface to the dermis

Illustration of a woman’s face with dotted lines and points from the cheeks to the chin

Watercolour portrait of a woman with soft light across her cheek

Personalised assessment

Who is PDRN recommended for?

PDRN is often recommended for skin that looks tired or dull, feels sensitive, or is showing early signs of ageing. Your doctor assesses your skin first to confirm PDRN suits your concerns and whether another treatment should be added.

Fish allergy, pregnancy or a skin infection? Tell your doctor first.

  • Dull or uneven skin tone

    Skin that looks tired or dull, whether it is dry or oily, or has an uneven tone.

  • Fine lines & early ageing

    Fine lines or early signs of ageing, as PDRN improves skin texture and elasticity.

  • Acne scarring & enlarged pores

    Acne scarring and enlarged pores, where supporting skin repair helps improve texture.

  • Sensitive or weakened skin

    Skin that has become more sensitive or weakened over time.

  • Long-term skin health

    People who want to maintain skin health as part of their long-term skincare routine.

PDRN injection at a glance
Topic What to expect thenGood to know
Treatment time Around 45 minutes, including time for numbing. Topical anaesthesia minimises discomfort.
How it’s given Tiny injections into the superficial layer of the skin. By fine needle or injector gun.
Course Usually 3–4 sessions, 3–4 weeks apart. Depends on your skin condition.
Maintenance 1 session every 6 months. Advised once the initial course is complete.
Downtime Minimal. Tiny bumps or mild redness may appear at the injection sites. These usually subside within a few hours to a day or two.
Combining Can be combined with laser or fillers. Planned after a detailed consultation.
Private consultation room with a round table and cushioned chairs at Fusion Medical
Patient’s cheek being examined under a lighted magnifier

Your treatment journey

Detailed consultation. Gentle injections. Planned maintenance.

  1. Consult

    We begin with a detailed consultation to assess your skin’s needs and decide whether PDRN, alone or with other treatments, suits you.

  2. Prepare

    Topical anaesthesia (numbing cream) is applied to minimise discomfort.

  3. Treat

    PDRN is administered into the superficial layer of the skin with an injector gun or fine needle. The visit takes around 45 minutes, including numbing.

  4. Recover

    Tiny bumps or mild redness usually subside within a few hours to a day or two. Sessions are 3–4 weeks apart, then every 6 months for maintenance.

Safety & expectations

Suitability comes first: a detailed consultation assesses your skin’s needs before any PDRN injection.

Tiny bumps or mild redness at the injection sites are expected and usually settle within a few hours to a day or two. Tell your doctor about any fish allergy, medicines, skin conditions or recent treatments.

PDRN Injectable (Salmon DNA): frequently asked questions

What is a PDRN injection made from?

A PDRN injection is made from polydeoxyribonucleotide (PDRN): salmon-derived DNA fragments, from a source known to be biocompatible with human skin. Injected into the superficial layer of the skin, these molecules help support its natural healing and regeneration process.

How many PDRN sessions do I need?

A course of 3–4 PDRN sessions at 3–4 week intervals is usually advised, depending on your skin condition, followed by 1 session every 6 months for maintenance. Your doctor will confirm the plan at your consultation.

What can I expect during PDRN treatment?

Topical anaesthesia is applied first to minimise any discomfort, after which PDRN is administered into your skin via an injector gun. The entire treatment takes around 45 minutes, including time for numbing, and is relatively quick and well tolerated.

Is there downtime after a PDRN injection?

Downtime is generally minimal. You might notice tiny bumps or mild redness at the injection sites immediately after PDRN treatment. These typically subside within a few hours to a day or two, so you can return to your daily activities relatively quickly.

Can PDRN help acne scars and enlarged pores?

PDRN is often recommended for acne scarring and enlarged pores, as well as dull or uneven skin tone and skin that has become sensitive or weakened. By supporting skin repair and regeneration, it helps improve texture and elasticity. Your doctor assesses your scars first and may combine PDRN with laser.

What is the difference between PDRN and PN injections?

Both are DNA-derived skin boosters, but they are different products and not interchangeable. Our PDRN injectable uses DNA fragments derived from salmon, given as tiny injections into the superficial layer of the skin, usually as 3–4 sessions 3–4 weeks apart. Our PN injectable uses polynucleotides extracted from Italian trout with patented Highly Purified Technology (HPT), usually as 3 sessions. Your doctor will recommend the one that suits your skin.

Can PDRN be combined with other treatments?

Yes. PDRN can be combined with other aesthetic treatments such as laser or fillers to enhance your results. We begin with a detailed consultation to assess your skin’s needs and determine suitable treatment options, so your plan is personalised.

Who should not have PDRN injections?

Because PDRN is derived from salmon DNA, tell your doctor if you have a fish allergy. Treatment may also be postponed if you are pregnant or breastfeeding or have an active skin infection in the area. Your doctor reviews your medical history, medicines and previous injections before PDRN treatment.

Appointments

Ready to explore what PDRN can do for your skin?

Book a consultation today. We’ll assess your skin’s needs and recommend suitable treatment options for you.

501 Orchard Road, #04-11 Wheelock Place, Singapore 238880 · Mon–Fri 8:30am–5:30pm · Sat 8:30am–1pm