
Salmon DNA fragments
The active ingredient is polydeoxyribonucleotide: DNA fragments derived from salmon.
Salmon DNA skin booster · Singapore
If your skin is feeling tired, dull or showing signs of ageing, PDRN may be the gentle skin-repairing treatment you’ve been looking for.
Salmon DNA fragments to support skin repair.
PDRN injections use fragments of DNA derived from salmon, a source known for its biocompatibility with human skin. Placed in the superficial layer of the skin, these molecules help support its natural healing and regeneration process, to improve skin quality from within.
PDRN stands for polydeoxyribonucleotide. It is often recommended when skin has become dull, sensitive or weakened over time, and some people use it to maintain skin health as part of a long-term skincare routine.
If you are comparing it with our PN injectable (polynucleotides from Italian trout), the FAQ below sets out how the two differ. Your doctor will explain which one suits your skin.
How it works
PDRN places fragments of salmon DNA in the superficial layer of the skin, where they help support its natural healing and regeneration process. Over a course of treatments, the aim is better skin quality (texture, elasticity, hydration and radiance) rather than instant volume.

Salmon DNA fragments
The active ingredient is polydeoxyribonucleotide: DNA fragments derived from salmon.

Supports repair and regeneration
These molecules help support your skin’s natural healing and regeneration process, improving skin quality from within.

Fine needle or injector gun
Tiny injections place PDRN in the superficial layer of the skin, by fine needle or injector gun. The procedure is relatively quick and well tolerated, and a numbing cream is usually applied first.

A course, then maintenance
Usually 3–4 sessions at 3–4 week intervals, depending on your skin condition, then 1 session every 6 months to maintain skin health.
Personalised assessment
PDRN is often recommended for skin that looks tired or dull, feels sensitive, or is showing early signs of ageing. Your doctor assesses your skin first to confirm PDRN suits your concerns and whether another treatment should be added.
Fish allergy, pregnancy or a skin infection? Tell your doctor first.
Skin that looks tired or dull, whether it is dry or oily, or has an uneven tone.
Fine lines or early signs of ageing, as PDRN improves skin texture and elasticity.
Acne scarring and enlarged pores, where supporting skin repair helps improve texture.
Skin that has become more sensitive or weakened over time.
People who want to maintain skin health as part of their long-term skincare routine.


Your treatment journey
We begin with a detailed consultation to assess your skin’s needs and decide whether PDRN, alone or with other treatments, suits you.
Topical anaesthesia (numbing cream) is applied to minimise discomfort.
PDRN is administered into the superficial layer of the skin with an injector gun or fine needle. The visit takes around 45 minutes, including numbing.
Tiny bumps or mild redness usually subside within a few hours to a day or two. Sessions are 3–4 weeks apart, then every 6 months for maintenance.
Safety & expectations
Suitability comes first: a detailed consultation assesses your skin’s needs before any PDRN injection.
Tiny bumps or mild redness at the injection sites are expected and usually settle within a few hours to a day or two. Tell your doctor about any fish allergy, medicines, skin conditions or recent treatments.
A PDRN injection is made from polydeoxyribonucleotide (PDRN): salmon-derived DNA fragments, from a source known to be biocompatible with human skin. Injected into the superficial layer of the skin, these molecules help support its natural healing and regeneration process.
A course of 3–4 PDRN sessions at 3–4 week intervals is usually advised, depending on your skin condition, followed by 1 session every 6 months for maintenance. Your doctor will confirm the plan at your consultation.
Topical anaesthesia is applied first to minimise any discomfort, after which PDRN is administered into your skin via an injector gun. The entire treatment takes around 45 minutes, including time for numbing, and is relatively quick and well tolerated.
Downtime is generally minimal. You might notice tiny bumps or mild redness at the injection sites immediately after PDRN treatment. These typically subside within a few hours to a day or two, so you can return to your daily activities relatively quickly.
PDRN is often recommended for acne scarring and enlarged pores, as well as dull or uneven skin tone and skin that has become sensitive or weakened. By supporting skin repair and regeneration, it helps improve texture and elasticity. Your doctor assesses your scars first and may combine PDRN with laser.
Both are DNA-derived skin boosters, but they are different products and not interchangeable. Our PDRN injectable uses DNA fragments derived from salmon, given as tiny injections into the superficial layer of the skin, usually as 3–4 sessions 3–4 weeks apart. Our PN injectable uses polynucleotides extracted from Italian trout with patented Highly Purified Technology (HPT), usually as 3 sessions. Your doctor will recommend the one that suits your skin.
Yes. PDRN can be combined with other aesthetic treatments such as laser or fillers to enhance your results. We begin with a detailed consultation to assess your skin’s needs and determine suitable treatment options, so your plan is personalised.
Because PDRN is derived from salmon DNA, tell your doctor if you have a fish allergy. Treatment may also be postponed if you are pregnant or breastfeeding or have an active skin infection in the area. Your doctor reviews your medical history, medicines and previous injections before PDRN treatment.
Doctor-led care
Appointments
Book a consultation today. We’ll assess your skin’s needs and recommend suitable treatment options for you.